Secreted factors from olfactory mucosa cells expanded as free-floating spheres increase neurogenesis in olfactory bulb neurosphere cultures
نویسندگان
چکیده
منابع مشابه
BDNF signaling during olfactory bulb neurogenesis.
Editor's Note: These short, critical reviews of recent papers in the Journal, written exclusively by graduate students or postdoctoral fellows, are intended to summarize the important findings of the paper and provide additional insight and commentary. For more information on the format and purpose of the Journal Club, please see Review of Bath et al. One of the most prominent sites of cell ren...
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The dentate gyrus (DG) and the olfactory bulb (OB) are two regions of the adult brain in which new neurons are integrated daily in the existing networks. It is clearly established that these newborn neurons are implicated in specific functions sustained by these regions and that different factors can influence neurogenesis in both structures. Among these, life events, particularly occurring dur...
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Olfactory mucosa was excised from the heads of embryonic day 15 (E15) rat fetuses, prior to the appearance of olfactory marker protein (OMP), and cultured with or without the presumptive olfactory bulb. Specific immunohistochemical staining for the OMP was detected in both groups of explants 6 days after explantation. At no time do the supporting cells and basal cells show positive OMP staining...
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ژورنال
عنوان ژورنال: BMC Neuroscience
سال: 2008
ISSN: 1471-2202
DOI: 10.1186/1471-2202-9-24